MBNL1 Polyclonal Antibody | G-AB-12014

MBNL1 Polyclonal Antibody | G-AB-12014 | Gentaur Antibodies

Overview: This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: MBNL1, EXP, MBNL

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 4154

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human MBNL1 (NP_066368.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9NR56

Santa Cruz:

Calculated MW: 33 kDa/34 kDa/36 kDa/37 kDa/39 kDa/40 kDa/41 kDa

Observed MW: 42 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MBNL1 Polyclonal Antibody DataSheet