MCM7 Polyclonal Antibody | G-AB-07540
Gentaur Antibodies
- SKU:
- G-AB-07540
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
MCM7 Polyclonal Antibody | G-AB-07540 | Gentaur Antibodies
Overview: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Category Type: Polyclonal Antibody
Research Areas: Epigenetics and Nuclear Signaling
Synonyms: MCM7, CDC47, MCM2, P1.1-MCM3, P1CDC47, P85MCM, PNAS146, PPP1R104
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Gene ID: 4176
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human MCM7 (NP_005907.3) .
Clone #:
Conjugation: Unconjugated
Swissprot: P33993
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IF
Dilution: IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.