MEP1B Polyclonal Antibody | G-AB-07306

MEP1B Polyclonal Antibody | G-AB-07306 | Gentaur Antibodies

Overview: Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: MEP1B

Reactivity: Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 4225

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human MEP1B (NP_005916.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q16820

Santa Cruz:

Calculated MW: 79 kDa

Observed MW: 105 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:1000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MEP1B Polyclonal Antibody DataSheet