METAP2 Polyclonal Antibody | G-AB-10908

METAP2 Polyclonal Antibody | G-AB-10908 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction

Synonyms: METAP2, MAP2, MNPEP, p67eIF2

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 10988

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human METAP2 (NP_006829.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P50579

Santa Cruz:

Calculated MW: 50 kDa/52 kDa

Observed MW: 60 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:200-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

METAP2 Polyclonal Antibody DataSheet