MGP Polyclonal Antibody | G-AB-06416

MGP Polyclonal Antibody | G-AB-06416 | Gentaur Antibodies

Overview: Matrix Gla protein (MGP) is is a vitamin K-dependent, extracellular matrix protein. MGP plays a pivotal role in preventing soft tissue calcification and local mineralization of the vascular wall. Vitamin K deficiency leads to inactive uncarboxylated MGP (ucMGP) , which accumulates at sites of arterial calcification. However MGP is synthesized in many tissues and is especially enriched in embryonic tissues and in cancer cells. Defects in MGP are the cause of Keutel syndrome (KS) , which is an autosomal recessive disorder characterized by abnormal cartilage calcification, peripheral pulmonary stenosis neural hearing loss and midfacial hypoplasia.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: Cell growth inhibiting gene 36 protein, Cell growth-inhibiting gene 36 protein, GAMMA-CARBOXYGLUTAMIC ACID PROTEIN, MATRIX, GIG36, Matrix Gla protein, MGLAP, MGP, MGP, NTI

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC005272

Clonality: Polyclonal

Immunogen: Fusion protein of human MGP

Clone #:

Conjugation: Unconjugated

Swissprot: P08493

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 0.84 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MGP Polyclonal Antibody DataSheet