MICA Polyclonal Antibody | G-AB-08477

MICA Polyclonal Antibody | G-AB-08477 | Gentaur Antibodies

Overview: This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Immunology

Synonyms: MICA, MIC-A, PERB11.1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 100507436

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human MICA (NP_000238.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q29983

Santa Cruz:

Calculated MW: 31 kDa/42 kDa

Observed MW: 43 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MICA Polyclonal Antibody DataSheet