MID1 Polyclonal Antibody | G-AB-11607

MID1 Polyclonal Antibody | G-AB-11607 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Alternative promoter use, alternative splicing and alternative polyadenylation result in multiple transcript variants that have different tissue specificities.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology

Synonyms: MID1, BBBG1, FXY, GBBB1, MIDIN, OGS1, OS, OSX, RNF59, TRIM18, XPRF, ZNFXY, midline 1

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 4281

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human MID1 (NP_000372.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: O15344

Santa Cruz:

Calculated MW: 62 kDa/75 kDa

Observed MW: 75-85 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MID1 Polyclonal Antibody DataSheet