MMP1 Polyclonal Antibody | G-AB-07647

MMP1 Polyclonal Antibody | G-AB-07647 | Gentaur Antibodies

Overview: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs) . Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD) . Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Cardiovascular, Signal Transduction

Synonyms: MMP1, CLG, CLGN

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 4312

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human MMP1 (NP_002412.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P03956

Santa Cruz:

Calculated MW: 54 kDa

Observed MW: 54 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MMP1 Polyclonal Antibody DataSheet