MMP11 Polyclonal Antibody | G-AB-03327

MMP11 Polyclonal Antibody | G-AB-03327 | Gentaur Antibodies

Overview: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Cardiovascular, Signal Transduction

Synonyms: Matrix Metalloproteinase 11, Matrix metalloproteinase-11, MMP-11, Mmp11, MMP11, SL 3, SL-3, SL3, ST3, STMY3, Stromelysin 3, Stromelysin III, Stromelysin-3

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: AAH57788

Clonality: Polyclonal

Immunogen: Synthetic peptide of human MMP11

Clone #:

Conjugation: Unconjugated

Swissprot: P24347

Santa Cruz:

Calculated MW: 55 kDa

Observed MW:

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MMP11 Polyclonal Antibody DataSheet