MMP25 Polyclonal Antibody | G-AB-01344

MMP25 Polyclonal Antibody | G-AB-01344 | Gentaur Antibodies

Overview: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Signal Transduction

Synonyms: Leukolysin, matrix metallopeptidase 25, matrix metallopeptidase like 1, matrix metalloproteinase 20, Matrix Metalloproteinase 25, Matrix metalloproteinase 25 precursor, Matrix metalloproteinase-25, Membrane type 6 Matrix Metalloproteinase, Membrane type Matrix Metalloproteinase 6, Membrane-type matrix metalloproteinase 6, Membrane-type-6 matrix metalloproteinase, MMP 25, MMP-25, MMP20, MMP20A, MMP25, MMP25, MMPL1, MT-MMP 6, MT6-MMP, MT6MMP, MTMMP6

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_071913

Clonality: Polyclonal

Immunogen: Synthetic peptide of human MMP25

Clone #:

Conjugation: Unconjugated

Swissprot: Q9NPA2

Santa Cruz: sc-20916/sc-20915/sc-25530

Calculated MW:

Observed MW:

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MMP25 Polyclonal Antibody DataSheet