MORF4L2 Polyclonal Antibody | G-AB-04879
Gentaur Antibodies
- SKU:
- G-AB-04879
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
MORF4L2 Polyclonal Antibody | G-AB-04879 | Gentaur Antibodies
Overview: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism
Synonyms: KIAA0026, MO4L2, MORF related gene X protein, MORF-related gene X protein, Morf4l2, MORFL2, Mortality factor 4 like protein 2, Mortality factor 4-like protein 2, MRGX, MSL3 2 protein, Protein MSL3-2, Transcription factor like protein MRGX, Transcription factor-like protein MRGX
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: NP036418
Clonality: Polyclonal
Immunogen: Synthetic peptide of human MORF4L2
Clone #:
Conjugation: Unconjugated
Swissprot: Q15014
Santa Cruz:
Calculated MW: 32 kDa
Observed MW: Refer to figures
Concentration: 0.7 mg/mL
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification method: Antigen affinity purification
Application: WB, IHC, ELISA
Dilution: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
Storage: Store at -20°C. Avoid freeze / thaw cycles.