MORF4L2 Polyclonal Antibody | G-AB-11761

MORF4L2 Polyclonal Antibody | G-AB-11761 | Gentaur Antibodies

Overview: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism

Synonyms: MORF4L2, MORFL2, MRGX

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 9643

Accession #:

Clonality:

Immunogen: A synthetic peptide of human MORF4L2 (NP_001135890.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q15014

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MORF4L2 Polyclonal Antibody DataSheet