MPG Polyclonal Antibody | G-AB-10639

MPG Polyclonal Antibody | G-AB-10639 | Gentaur Antibodies

Overview: Maintenance of DNA sequences is necessary for vertebrates and other life. DNA is under constant stress by a plethora of DNA-damaging agents present in both the environment and within cells. The potentially deleterious effects of DNA lesions in cells are elegantly resolved by sophisticated DNA repair systems, including base excision repair (BER) , nucleotide excision repair (NER) and DNA repair methyltransferase (MTase) . Methylated bases, such as 3-methyladenine (3MeA) and 7-methylguanine (7MeG) can be formed by agents in the environment and by endogenous cellular processes. Consequently, in the absence of exposure to environmental agents, DNA methylation damage can be incurred on the genomic DNA of normal mammalian cells. DNA N-glycosylases are base excision-repair proteins that locate and cleave damaged bases from DNA as the first step in restoring the sequence.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling

Synonyms: MPG, AAG, ADPG, APNG, CRA36.1, MDG, Mid1, PIG11, PIG16, anpg

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 4350

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human MPG (NP_001015052.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P29372

Santa Cruz:

Calculated MW: 30 kDa/32 kDa

Observed MW: 37 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

MPG Polyclonal Antibody DataSheet