NCR2 Polyclonal Antibody | G-AB-03084

NCR2 Polyclonal Antibody | G-AB-03084 | Gentaur Antibodies

Overview: Natural cytotoxicity triggering receptor 2is aproteinthat in humans is encoded by theNCR2gene. NCR2 has also been designated asCD336 (cluster of differentiation336) . NKp44 is a natural cytotoxicity receptor that is is expressed on IL-2-activated human NK cells and may contribute to the increased efficiency of NK cells to mediate tumor cell lysis. NKp44 is composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain. Prolactin up-regulates and cortisol down-regulates the surface expression of NKp44 at the transcriptional level. A cellular ligand for NKp44 (NKp44L) is expressed during HIV-1 infection and is correlated with the progression of CD4+ T cell depletion and an increase of viral load.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Immunology, Signal Transduction

Synonyms: Activating NK receptor NKp44, CD336, CD336 antigen, dJ149M18.1, LY95, Lymphocyte antigen 95 (activating NK receptor, NK p44) , Lymphocyte antigen 95 homolog (activating NK receptor, NK p44) , Lymphocyte antigen 95 homolog, Lymphocyte antigen 95, mouse, homolog of, Natural cytotoxicity triggering receptor 2, Natural killer cell p44 related protein, Natural killer cell p44-related protein, NCR2, NCTR2, NK cell activating receptor (NKp44) , NK cell activating receptor, NK cell-activating receptor, NK p44, NK-p44, NKp44

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_001186438

Clonality: Polyclonal

Immunogen: Synthetic peptide of human NCR2

Clone #:

Conjugation: Unconjugated

Swissprot: O95944

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

NCR2 Polyclonal Antibody DataSheet