NEB Polyclonal Antibody | G-AB-01445

NEB Polyclonal Antibody | G-AB-01445 | Gentaur Antibodies

Overview: This gene encodes nebulin, a giant protein component of the cytoskeletal matrix that coexists with the thick and thin filaments within the sarcomeres of skeletal muscle. In most vertebrates, nebulin accounts for 3 to 4% of the total myofibrillar protein. The encoded protein contains approximately 30-amino acid long modules that can be classified into 7 types and other repeated modules. Protein isoform sizes vary from 600 to 800 kD due to alternative splicing that is tissue-, species-, and developmental stage-specific. Of the 183 exons in the nebulin gene, at least 43 are alternatively spliced, although exons 143 and 144 are not found in the same transcript. Of the several thousand transcript variants predicted for nebulin, the RefSeq Project has decided to create three representative RefSeq records. Mutations in this gene are associated with recessive nemaline myopathy.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: DKFZp686C1456, FLJ11505, FLJ36536, FLJ39568, FLJ39584, NEB 177D, NEB, NEB177D, NEBU, Nebulin, NEM 2, NEM2

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_001157979

Clonality: Polyclonal

Immunogen: Synthetic peptide of human NEB

Clone #:

Conjugation: Unconjugated

Swissprot: P20929

Santa Cruz: sc-8083/sc-8082/sc-28286

Calculated MW:

Observed MW:

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

NEB Polyclonal Antibody DataSheet