NPHS1 Polyclonal Antibody | G-AB-10255

NPHS1 Polyclonal Antibody | G-AB-10255 | Gentaur Antibodies

Overview: This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction

Synonyms: NPHS1, CNF, NPHN, nephrin

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 4868

Accession #:

Clonality:

Immunogen: A synthetic peptide of human NPHS1

Clone #:

Conjugation: Unconjugated

Swissprot: O60500

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:100 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

NPHS1 Polyclonal Antibody DataSheet