NQO1 Polyclonal Antibody | G-AB-02907

NQO1 Polyclonal Antibody | G-AB-02907 | Gentaur Antibodies

Overview: This gene is a member of the NAD (P) H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD) , an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD) . Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction

Synonyms: Azoreductase, Cytochrome b 5 reductase, DHQU, DIA 4, DIA4, Diaphorase (NADH/NADPH) (cytochrome b 5 reductase) , Diaphorase (NADH/NADPH) , Diaphorase 4, Dioxin inducible 1, DT diaphorase, DT-diaphorase, DTD, Menadione reductase, NAD (P) H dehydrogenase [quinone] 1, NAD (P) H dehydrogenase quinone 1, NAD (P) H menadione oxidoreductase 1 dioxin inducible, NAD (P) H quinone dehydrogenase 1, NAD (P) H: menadione oxidoreductase 1 dioxin inducible 1, NAD (P) H:menadione oxidoreductase 1, NAD (P) H:Quinone acceptor oxidoreductase type 1, NAD (P) H:quinone oxidoreductase 1, NAD (P) H:quinone oxireductase, NMOR 1, NMOR I, NMOR1, NMORI, NQO 1, NQO1, NQO1, Phylloquinone reductase, QR 1, QR1, Quinone reductase 1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_001020604

Clonality: Polyclonal

Immunogen: Synthetic peptide of human NQO1

Clone #:

Conjugation: Unconjugated

Swissprot: P15559

Santa Cruz: sc-16464/sc-16463/sc-25591

Calculated MW: 27 kDa

Observed MW:

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, ELISA

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

NQO1 Polyclonal Antibody DataSheet