NUDT15 Polyclonal Antibody | G-AB-12162
Gentaur Antibodies
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Gentaur Antibodies
NUDT15 Polyclonal Antibody | G-AB-12162
- SKU:
- G-AB-12162
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
NUDT15 Polyclonal Antibody | G-AB-12162 | Gentaur Antibodies
Overview: This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified.
Category Type: Polyclonal Antibody
Research Areas: Epigenetics and Nuclear Signaling
Synonyms: NUDT15, MTH2, NUDT15D
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 55270
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human NUDT15 (NP_060753.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: Q9NV35
Santa Cruz:
Calculated MW: 18 kDa
Observed MW: 19 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IHC
Dilution: WB 1:500-1:2000 IHC 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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