OGG1 Polyclonal Antibody | G-AB-08449

OGG1 Polyclonal Antibody | G-AB-08449 | Gentaur Antibodies

Overview: This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: OGG1, HMMH, HOGG1, MUTM, OGH1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 4968

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human OGG1 (NP_002533.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: O15527

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

OGG1 Polyclonal Antibody DataSheet