OPRK1 Polyclonal Antibody | G-AB-08544

OPRK1 Polyclonal Antibody | G-AB-08544 | Gentaur Antibodies

Overview: This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

Category Type: Polyclonal Antibody

Research Areas: Neuroscience

Synonyms: OPRK1, K-OR-1, KOR, KOR-1, OPRK

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 4986

Accession #:

Clonality:

Immunogen: A synthetic peptide of human OPRK1 (NP_000903.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P41145

Santa Cruz:

Calculated MW: 33 kDa/42 kDa

Observed MW: 40 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000 IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

OPRK1 Polyclonal Antibody DataSheet