OTX2 Polyclonal Antibody | G-AB-08545

OTX2 Polyclonal Antibody | G-AB-08545 | Gentaur Antibodies

Overview: This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6) . This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Developmental Biology, Neuroscience, Stem Cells

Synonyms: OTX2, CPHD6, MCOPS5

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 5015

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human OTX2 (NP_068374.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P32243

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:100 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

OTX2 Polyclonal Antibody DataSheet