PDE6B Polyclonal Antibody | G-AB-11389
Gentaur Antibodies
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Gentaur Antibodies
PDE6B Polyclonal Antibody | G-AB-11389
- SKU:
- G-AB-11389
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
PDE6B Polyclonal Antibody | G-AB-11389 | Gentaur Antibodies
Overview: Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE) , resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
Category Type: Polyclonal Antibody
Research Areas:
Synonyms: PDE6B, CSNB3, CSNBAD2, PDEB, RP40, rd1, GMP-PDEbeta
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 5158
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human PDE6B (NP_001138763.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: P35913
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IHC
Dilution: IHC 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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