PERK Polyclonal Antibody | G-AB-05490
Gentaur Antibodies
- SKU:
- G-AB-05490
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
PERK Polyclonal Antibody | G-AB-05490 | Gentaur Antibodies
Overview: The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2) , leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER) , where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism
Synonyms: DKFZp781H1925, E2AK3, EC 2.7.11.1, Eif2ak3, Eukaryotic translation initiation factor 2 alpha kinase 3, Eukaryotic translation initiation factor 2-alpha kinase 3, Heme regulated EIF2 alpha kinase, HRI, HsPEK, Pancreatic eIF2 alpha kinase, Pancreatic eIF2-alpha kinase, PEK, PRKR like endoplasmic reticulum kinase, PRKR-like endoplasmic reticulum kinase, WRS
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #:
Clonality: Polyclonal
Immunogen: KLH conjugated Synthetic peptide corresponding to Human PERK
Clone #:
Conjugation: Unconjugated
Swissprot: Q9NZJ5
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1.4 mg/mL
Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Purification method: Affinity purification
Application: IHC
Dilution: IHC 1:400-1000
Storage: Store at -20°C. Avoid freeze / thaw cycles.