PFN2 Polyclonal Antibody | G-AB-01377

PFN2 Polyclonal Antibody | G-AB-01377 | Gentaur Antibodies

Overview: The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: D3S1319E, PFL, PFN 2, Pfn2, PROF2, Profilin II, Profilin-2, Profilin2, ProfilinII

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_444252

Clonality: Polyclonal

Immunogen: Synthetic peptide of human PFN2

Clone #:

Conjugation: Unconjugated

Swissprot: P35080

Santa Cruz:

Calculated MW: 15 kDa

Observed MW:

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PFN2 Polyclonal Antibody DataSheet