PHF21A Polyclonal Antibody | G-AB-11030

PHF21A Polyclonal Antibody | G-AB-11030 | Gentaur Antibodies

Overview: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. PHF21A (PHD finger protein 21A) , also known as BRAF35-HDAC complex protein BHC80, is a 680 amino acid nuclear protein that contains one PHD-type zinc finger and one A.T hook DNA-binding domain, suggesting involvement in transcriptional regulation events. PHF21A is a component of the BHC complex, which is responsible for repressing transcription of neuron-specific genes in non-neuronal cells. The BHC complex acts as a chromatin modifier that deacetylates and demethylates specific sites on histones. PHF21A may act as a scaffold within the BHC complex. Predominantly expressed in brain, three isoforms of PHF21A exist as a result of alternative splicing events.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling, Neuroscience

Synonyms: PHF21A, BHC80, BM-006

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 51317

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human PHF21A (NP_001095272.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q96BD5

Santa Cruz:

Calculated MW: 70 kDa/74 kDa

Observed MW: 70-80 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PHF21A Polyclonal Antibody DataSheet