Phospho-p53 (S15) Polyclonal Antibody | G-AB-12614

Phospho-p53 (S15) Polyclonal Antibody | G-AB-12614 | Gentaur Antibodies

Overview: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277) .

Category Type: Phosphorylated antibody

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Synonyms: BCC7, LFS1, P53, TRP53, p53, TP53, BMFS5

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 7157

Accession #:

Clonality:

Immunogen: A phospho specific peptide corresponding to residues surrounding S15 of human p53.

Clone #:

Conjugation: Unconjugated

Swissprot: P04637

Santa Cruz:

Calculated MW: 43 kDa

Observed MW: 53 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Phospho-p53 (S15) Polyclonal Antibody DataSheet