Phospho-PAK1 (Thr212) Polyclonal Antibody | G-AB-05774

Phospho-PAK1 (Thr212) Polyclonal Antibody | G-AB-05774 | Gentaur Antibodies

Overview: The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.

Category Type: Phosphorylated antibody

Research Areas: Cancer, Cell Biology, Signal Transduction

Synonyms: ADRB2, Alpha PAK, Alpha-PAK, MGC130000, MGC130001, p21 activated kinase 1, p21 protein (Cdc42/Rac) activated kinase 1, p21-activated kinase 1, p21/Cdc42/Rac1 activated kinase 1 (yeast Ste20 related) , p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) , p65 PAK, p65-PAK, P68-PAK, PAK alpha, PAK-1, Pak1, PAK1, Paka, PAKalpha, Protein kinase MUK2, Rac/p21-activated kinase, Serine/threonine-protein kinase PAK 1, STE20 homolog yeast

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human PAKα around the phosphorylation site of Thr212

Clone #:

Conjugation: Unconjugated

Swissprot: Q13153

Santa Cruz:

Calculated MW: 61 kDa

Observed MW: 65 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification method: Affinity purification

Application: WB, IHC-p, ELISA

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Phospho-PAK1 (Thr212) Polyclonal Antibody DataSheet