PIM1 Polyclonal Antibody | G-AB-08609
Gentaur Antibodies
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Gentaur Antibodies
PIM1 Polyclonal Antibody | G-AB-08609
- SKU:
- G-AB-08609
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
PIM1 Polyclonal Antibody | G-AB-08609 | Gentaur Antibodies
Overview: The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in Signal Transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810) .
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction, Stem Cells
Synonyms: PIM, PIM1, PIM1
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 5292
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human PIM1 (NP_002639.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: P11309
Santa Cruz:
Calculated MW: 35 kDa/45 kDa
Observed MW: 35 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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