PLAT Polyclonal Antibody | G-AB-01497

PLAT Polyclonal Antibody | G-AB-01497 | Gentaur Antibodies

Overview: This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Cardiovascular, Metabolism

Synonyms: Alteplase, DKFZp686I03148, Plasminogen activator tissue, Plasminogen activator tissue type, PLAT, Reteplase, t PA, T Plasminogen Activator, t-PA, T-plasminogen activator, Tissue plasminogen activator (t PA) , Tissue type plasminogen activator, Tissue-type plasminogen activator chain B, tPA, TPA, TPA1

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_000921

Clonality: Polyclonal

Immunogen: Synthetic peptide of human PLAT

Clone #:

Conjugation: Unconjugated

Swissprot: P00750

Santa Cruz: sc-5239/sc-5241/sc-59721/sc-15346

Calculated MW: 63 kDa

Observed MW:

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:200-1:1000, IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PLAT Polyclonal Antibody DataSheet