PPARA Polyclonal Antibody | G-AB-09766

PPARA Polyclonal Antibody | G-AB-09766 | Gentaur Antibodies

Overview: Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction

Synonyms: PPAR, NR1C1, hPPAR, PPARalpha, PPAR alpha, PPARA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 5465

Accession #:

Clonality:

Immunogen: Recombinant protein of human PPARA.

Clone #:

Conjugation: Unconjugated

Swissprot: Q07869

Santa Cruz:

Calculated MW: 52 kDa

Observed MW: 52 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PPARA Polyclonal Antibody DataSheet