PPARD Polyclonal Antibody | G-AB-01474

PPARD Polyclonal Antibody | G-AB-01474 | Gentaur Antibodies

Overview: This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC) , a tumor suppressor protein related to APC/beta-catenin signaling pathway.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism

Synonyms: FAAR, MGC3931, NR1C2, NUC1, NUCI, NUCII, Nuclear hormone receptor 1, Nuclear receptor subfamily 1 group C member 2, Peroxisome proliferative activated receptor delta, Peroxisome proliferator-activated receptor beta (PPAR-beta) , Peroxisome proliferator-activated receptor beta, Peroxisome proliferator-activated receptor delta, PPAR beta, PPAR-beta, PPAR-delta, PPAR-, PPARB, ppard, PPARD

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_006229

Clonality: Polyclonal

Immunogen: Synthetic peptide of human PPARD

Clone #:

Conjugation: Unconjugated

Swissprot: Q03181

Santa Cruz: sc-1986/sc-1987/sc-1983/sc-7197

Calculated MW: 50 kDa

Observed MW:

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, ELISA

Dilution: WB 1:200-1:1000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PPARD Polyclonal Antibody DataSheet