PPM1M Polyclonal Antibody | G-AB-04598

PPM1M Polyclonal Antibody | G-AB-04598 | Gentaur Antibodies

Overview: PPM1M is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase was identified as an interacting protein of Rho guanine nucleotide exchange factors (PIX) . PIX proteins are regulators of p21/Cdc42/Rac1-activated kinase 1 (PAK1) , a protein kinase mediating biological effects downstream of Rho GTPases. This phosphatase has been shown to block the effects of PAK, and thus inhibit actin stress fiber breakdown and morphological changes driven by cell division cycle 42 (CDC42) .

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: FLJ32332, PP2C eta, PP2C-eta, PP2CE, PP2Ceta, PPM1M, PPM1M, protein phosphatase 1M (PP2C domain containing) , Protein phosphatase 1M, Protein phosphatase 2C isoform eta

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC009644

Clonality: Polyclonal

Immunogen: Fusion protein of human PPM1M

Clone #:

Conjugation: Unconjugated

Swissprot: Q96MI6

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1.74 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:100-1:300, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PPM1M Polyclonal Antibody DataSheet