PRDX3 Polyclonal Antibody | G-AB-08039

PRDX3 Polyclonal Antibody | G-AB-08039 | Gentaur Antibodies

Overview: This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction

Synonyms: PRDX3, AOP-1, AOP1, HBC189, MER5, PRO1748, SP-22, prx-III

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 10935

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human PRDX3 (NP_006784.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P30048

Santa Cruz:

Calculated MW: 25 kDa/27 kDa

Observed MW: 28 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PRDX3 Polyclonal Antibody DataSheet