PRKAG3 Polyclonal Antibody | G-AB-11706

PRKAG3 Polyclonal Antibody | G-AB-11706 | Gentaur Antibodies

Overview: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK) . AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR) , key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: PRKAG3, AMPKG3

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 53632

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human PRKAG3 (NP_059127.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9UGI9

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PRKAG3 Polyclonal Antibody DataSheet