PRKCE Polyclonal Antibody | G-AB-09947

PRKCE Polyclonal Antibody | G-AB-09947 | Gentaur Antibodies

Overview: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS) -mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction

Synonyms: PRKCE, PKCE, nPKC-epsilon

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 5581

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human PRKCE (NP_005391.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q02156

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PRKCE Polyclonal Antibody DataSheet