PRMT6 Polyclonal Antibody | G-AB-11881

PRMT6 Polyclonal Antibody | G-AB-11881 | Gentaur Antibodies

Overview: The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling

Synonyms: PRMT6, HRMT1L6

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 55170

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human PRMT6 (NP_060607.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q96LA8

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PRMT6 Polyclonal Antibody DataSheet