PSAP Polyclonal Antibody | G-AB-09758

PSAP Polyclonal Antibody | G-AB-09758 | Gentaur Antibodies

Overview: This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Category Type: Polyclonal Antibody

Research Areas: Metabolism, Signal Transduction

Synonyms: PSAP, GLBA, SAP1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 5660

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human PSAP (NP_002769.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P07602

Santa Cruz:

Calculated MW: 58 kDa

Observed MW: 58 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PSAP Polyclonal Antibody DataSheet