PSMB10 Polyclonal Antibody | G-AB-10662

PSMB10 Polyclonal Antibody | G-AB-10662 | Gentaur Antibodies

Overview: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Immunology

Synonyms: PSMB10, LMP10, MECL1, beta2i

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 5699

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human PSMB10 (NP_002792.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P40306

Santa Cruz:

Calculated MW: 28 kDa

Observed MW: 29 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PSMB10 Polyclonal Antibody DataSheet