PTAFR Polyclonal Antibody | G-AB-02915
Gentaur Antibodies
Write a Review
Gentaur Antibodies
PTAFR Polyclonal Antibody | G-AB-02915
- SKU:
- G-AB-02915
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
PTAFR Polyclonal Antibody | G-AB-02915 | Gentaur Antibodies
Overview: This gene encodes a seven-transmembrane G-protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that plays a significant role in oncogenic transformation, tumor growth, angiogenesis, metastasis, and pro-inflammatory processes. Binding of PAF to the PAF-receptor (PAFR) stimulates numerous Signal Transduction pathways including phospholipase C, D, A2, mitogen-activated protein kinases (MAPKs) , and the phosphatidylinositol-calcium second messenger system. Following PAFR activation, cells become rapidly desensitized and this refractory state is dependent on PAFR phosphorylation, internalization, and down-regulation. Alternative splicing results in multiple transcript variants.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular, Immunology, Signal Transduction
Synonyms: OTTHUMP00000004041, OTTMUSP00000010350, PAF R, PAF receptor, PAF-R, PAFr, Platelet activating factor receptor, Platelet-activating factor receptor, PTAFR, PTAFR, RP23-470B20.1
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: NP_000943
Clonality: Polyclonal
Immunogen: Synthetic peptide of human PTAFR
Clone #:
Conjugation: Unconjugated
Swissprot: P25105
Santa Cruz: sc-8741/sc-8742/sc-20732
Calculated MW:
Observed MW:
Concentration: 0.5 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: IHC, ELISA
Dilution: IHC 1:25-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Related Products
