PTN Polyclonal Antibody | G-AB-01477

PTN Polyclonal Antibody | G-AB-01477 | Gentaur Antibodies

Overview: Pleiotrophin (PTN) also known asheparin-binding brain mitogen (HBBM) orheparin-binding growth factor 8 (HBGF-8) orneurite growth-promoting factor 1 (NEGF1) orheparin affinity regulatory peptide (HARP) orheparin binding growth associated molecule (HB-GAM) is aproteinthat in humans is encoded by thePTNgene.Pleiotrophin is an 18-kDagrowth factorthat has a high affinity forheparin. It is structurally related tomidkineandretinoic acid induced heparin-binding protein. Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Immunology, Neuroscience, Signal Transduction

Synonyms: HARP, HB-GAM, HBBM, HBGAM, HBGF-8, HBGF8, HBNF, HBNF-1, HBNF1, heparin affin regulatory protein, Heparin binding growth associated molecule, Heparin binding growth factor 8, Heparin binding neurite outgrowth promoting factor 1, Heparin-binding brain mitogen, Heparin-binding growth factor 8, Heparin-binding growth-associated molecule, heparin-binding neurite outgrowth promoting factor, Heparin-binding neurite outgrowth-promoting factor 1, NEGF1, Neurite growth promoting factor 1, Neurite outgrowth-promoting factor, heparin-binding, OSF-1, OSF1, Osteoblast-specific factor 1, pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1) , Pleiotrophin, PTN, PTN

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_002816

Clonality: Polyclonal

Immunogen: Synthetic peptide of human PTN

Clone #:

Conjugation: Unconjugated

Swissprot: P21246

Santa Cruz: sc-1394/sc-1395/sc-20716

Calculated MW: 19 kDa

Observed MW:

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, ELISA

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

PTN Polyclonal Antibody DataSheet