RAD50 Polyclonal Antibody | G-AB-07120
Gentaur Antibodies
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Gentaur Antibodies
RAD50 Polyclonal Antibody | G-AB-07120
- SKU:
- G-AB-07120
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
RAD50 Polyclonal Antibody | G-AB-07120 | Gentaur Antibodies
Overview: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Synonyms: RAD50, NBSLD, RAD502, hRad50
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Gene ID: 10111
Accession #:
Clonality:
Immunogen: A synthetic peptide of human RAD50
Clone #:
Conjugation: Unconjugated
Swissprot: Q92878
Santa Cruz:
Calculated MW: 138 kDa/153 kDa/154 kDa
Observed MW: 180 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IHC
Dilution: WB 1:500-1:2000 IHC 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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