RASGRF1 Polyclonal Antibody | G-AB-11405

RASGRF1 Polyclonal Antibody | G-AB-11405 | Gentaur Antibodies

Overview: The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: RASGRF1, CDC25, CDC25L, GNRP, GRF1, GRF55, H-GRF55, PP13187, ras-GRF1

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 5923

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human RASGRF1 (NP_001139120.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q13972

Santa Cruz:

Calculated MW: 55 kDa/143 kDa/145 kDa

Observed MW: 145 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

RASGRF1 Polyclonal Antibody DataSheet