RASSF1 Polyclonal Antibody | G-AB-07681

RASSF1 Polyclonal Antibody | G-AB-07681 | Gentaur Antibodies

Overview: This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms: RASSF1, 123F2, NORE2A, RASSF1A, RDA32, REH3P21

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 11186

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human RASSF1 (NP_009113.3) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9NS23

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

RASSF1 Polyclonal Antibody DataSheet