RB1 Polyclonal Antibody | G-AB-08809

RB1 Polyclonal Antibody | G-AB-08809 | Gentaur Antibodies

Overview: The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB) , bladder cancer, and osteogenic sarcoma.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Synonyms: OSRC, PPP1R130, RB, p105-Rb, pRb, pp110, RB1, Rb

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 5925

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human RB1 (NP_000312.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P06400

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

RB1 Polyclonal Antibody DataSheet