RBM15 Polyclonal Antibody | G-AB-04288

RBM15 Polyclonal Antibody | G-AB-04288 | Gentaur Antibodies

Overview: RNA-binding motif protein 15 (RBM15) belongs to the SPEN protein family, which have repressor function in several signaling pathway, and may bind to RNA through interaction with spliceosome components. It was first described as a 5′ translocation partner of the MAL gene in t (1, 22) (p13;q13) infant acute megakaryocytic leukemia, and it functions in murine hematopoiesis through modulating Notch-induced transcriptional activation, which play crucial roles in leukemogenesis. Decreasing RBM15 levels with RNA interference could inhibit the growth and proliferation, block the cell cycle, and induce apoptosis in CML cells.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling, Stem Cells

Synonyms: One twenty two protein, One-twenty two protein 1, OTT, OTT1, Putative RNA-binding protein 15, RBM15, RBM15, RNA binding motif protein 15, RNA-binding motif protein 15

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC006397

Clonality: Polyclonal

Immunogen: Fusion protein of human RBM15

Clone #:

Conjugation: Unconjugated

Swissprot: Q96T37

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1.2 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

RBM15 Polyclonal Antibody DataSheet