RBM15 Polyclonal Antibody | G-AB-10539
Gentaur Antibodies
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Gentaur Antibodies
RBM15 Polyclonal Antibody | G-AB-10539
- SKU:
- G-AB-10539
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
RBM15 Polyclonal Antibody | G-AB-10539 | Gentaur Antibodies
Overview: RNA-binding motif protein 15 (RBM15) belongs to the SPEN protein family, which have repressor function in several signaling pathway, and may bind to RNA through interaction with spliceosome components. It was first described as a 5′ translocation partner of the MAL gene in t (1, 22) (p13;q13) infant acute megakaryocytic leukemia, and it functions in murine hematopoiesis through modulating Notch-induced transcriptional activation, which play crucial roles in leukemogenesis. Decreasing RBM15 levels with RNA interference could inhibit the growth and proliferation, block the cell cycle, and induce apoptosis in CML cells.
Category Type: Polyclonal Antibody
Research Areas: Epigenetics and Nuclear Signaling, Stem Cells
Synonyms: RBM15, OTT, OTT1, SPEN
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Gene ID: 64783
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human RBM15 (NP_001188474.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: Q96T37
Santa Cruz:
Calculated MW: 99 kDa/104 kDa/106 kDa/107 kDa
Observed MW: 120 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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