RBP3 Polyclonal Antibody | G-AB-11072

RBP3 Polyclonal Antibody | G-AB-11072 | Gentaur Antibodies

Overview: Interphotoreceptor retinol-binding protein is a large glycoprotein known to bind retinoids and found primarily in the interphotoreceptor matrix of the retina between the retinal pigment epithelium and the photoreceptor cells. It is thought to transport retinoids between the retinal pigment epithelium and the photoreceptors, a critical role in the visual process.The human IRBP gene is approximately 9.5 kbp in length and consists of four exons separated by three introns. The introns are 1.6-1.9 kbp long. The gene is transcribed by photoreceptor and retinoblastoma cells into an approximately 4.3-kilobase mRNA that is translated and processed into a glycosylated protein of 135, 000 Da. The amino acid sequence of human IRBP can be divided into four contiguous homology domains with 33-38% identity, suggesting a series of gene duplication events. In the gene, the boundaries of these domains are not defined by exon-intron junctions, as might have been expected. The first three homology domains and part of the fourth are all encoded by the first large exon, which is 3, 180 base pairs long. The remainder of the fourth domain is encoded in the last three exons, which are 191, 143, and approximately 740 base pairs long, respectively.

Category Type: Polyclonal Antibody

Research Areas: Neuroscience

Synonyms: RBP3, D10S64, D10S65, D10S66, IRBP, RBPI, RP66

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 5949

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human RBP3 (NP_002891.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P10745

Santa Cruz:

Calculated MW: 135 kDa

Observed MW: 180 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

RBP3 Polyclonal Antibody DataSheet