RHOB Polyclonal Antibody | G-AB-09539

RHOB Polyclonal Antibody | G-AB-09539 | Gentaur Antibodies

Overview: Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene.RHOB is a member of the Rho GTP-binding protein family.Mediates apoptosis in neoplastically transformed cells after DNA damage. It is not necessary for development but affects cell adhesion and growth factor signaling in transformed cells. It plays a negative role in tumorigenesis as deletion causes tumor formation. It involved in intracellular protein trafficking of a number of proteins, and serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: RHOB, ARH6, ARHB, MST081, MSTP081, RHOH6

Reactivity: Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 388

Accession #:

Clonality:

Immunogen: A synthetic peptide of human RHOB (NP_004031.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P62745

Santa Cruz:

Calculated MW: 22 kDa

Observed MW: 22 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

RHOB Polyclonal Antibody DataSheet