RRM2B Polyclonal Antibody | G-AB-12004

RRM2B Polyclonal Antibody | G-AB-12004 | Gentaur Antibodies

Overview: This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism

Synonyms: RRM2B, MTDPS8A, MTDPS8B, P53R2

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 50484

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human RRM2B (NP_056528.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q7LG56

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

RRM2B Polyclonal Antibody DataSheet