SAA1 Polyclonal Antibody | G-AB-06421

SAA1 Polyclonal Antibody | G-AB-06421 | Gentaur Antibodies

Overview: This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11. SAA1 (Serum Amyloid A1) is a Protein Coding gene. Diseases associated with SAA1 include Amyloidosis Aa and Splenic Artery Aneurysm. Among its related pathways are Peptide ligand-binding receptors and Activated TLR4 signalling. GO annotations related to this gene include heparin binding and chemoattractant activity. An important paralog of this gene is SAA2.

Category Type: Polyclonal Antibody

Research Areas: Cardiovascular, Metabolism, Immunology, Signal Transduction

Synonyms: amyloid A, serum, Amyloid fibril protein AA, Amyloid protein A, MGC111216, PIG4, SAA, SAA2, Serum amyloid A protein, serum amyloid A-1 protein, serum amyloid A1, TP53I4, Tumor protein p53 inducible protein 4

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC007022

Clonality: Polyclonal

Immunogen: Fusion protein of human SAA1

Clone #:

Conjugation: Unconjugated

Swissprot: P0DJI8

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1.2 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:100-1:300, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

SAA1 Polyclonal Antibody DataSheet